2BEH

Crystal structure of antithrombin variant S137A/V317C/T401C with plasma latent antithrombin

2BEH の概要

• エントリーDOI: 10.2210/pdb2beh/pdb
• 関連するPDBエントリー: 1T1F 1TB6 2B5T
• 分子名称: Antithrombin-III, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (7 entities in total)
• 機能のキーワード: antithrombin dimer, blood clotting
• 由来する生物種: Homo sapiens (human); 詳細
• 細胞内の位置: Secreted, extracellular space: P01008 P01008
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 100161.94

構造登録者

Johnson, D.J.,Luis, S.A.,Huntington, J.A. (登録日: 2005-10-24, 公開日: 2005-11-01, 最終更新日: 2021-10-20)

• 主引用文献: Johnson, D.J.,Langdown, J.,Li, W.,Luis, S.A.,Baglin, T.P.,Huntington, J.A.; Crystal structure of monomeric native antithrombin reveals a novel reactive center loop conformation.; J.Biol.Chem., 281:35478-35486, 2006; PubMed: 16973611; DOI: 10.1074/jbc.M607204200

実験手法

X-RAY DIFFRACTION (2.7 Å)