2BEC
Crystal structure of CHP2 in complex with its binding region in NHE1 and insights into the mechanism of pH regulation
Summary for 2BEC
Entry DOI | 10.2210/pdb2bec/pdb |
Descriptor | Calcineurin B homologous protein 2, Sodium/hydrogen exchanger 1, YTTRIUM (III) ION (3 entities in total) |
Functional Keywords | calcineurin-homologous protein, calcium-binding protein, nhe1 regulating protein, metal binding protein-transport protein complex, metal binding protein/transport protein |
Biological source | Homo sapiens (human) More |
Cellular location | Membrane; Multi-pass membrane protein: P19634 |
Total number of polymer chains | 2 |
Total formula weight | 28509.78 |
Authors | Ben Ammar, Y.,Takeda, S.,Hisamitsu, T.,Mori, H.,Wakabayashi, S. (deposition date: 2005-10-24, release date: 2006-06-27, Last modification date: 2024-03-13) |
Primary citation | Ben Ammar, Y.,Takeda, S.,Hisamitsu, T.,Mori, H.,Wakabayashi, S. Crystal structure of CHP2 complexed with NHE1-cytosolic region and an implication for pH regulation Embo J., 25:2315-2325, 2006 Cited by PubMed: 16710297DOI: 10.1038/sj.emboj.7601145 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.7 Å) |
Structure validation
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