2BBQ
STRUCTURAL BASIS FOR RECOGNITION OF POLYGLUTAMYL FOLATES BY THYMIDYLATE SYNTHASE
Summary for 2BBQ
Entry DOI | 10.2210/pdb2bbq/pdb |
Descriptor | THYMIDYLATE SYNTHASE, 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, 10-PARPARGYL-5,8-DIDEAZAFOLATE-4-GLUTAMIC ACID, ... (4 entities in total) |
Functional Keywords | transferase(methyltransferase) |
Biological source | Escherichia coli |
Cellular location | Cytoplasm: P0A884 |
Total number of polymer chains | 2 |
Total formula weight | 63377.29 |
Authors | Kamb, A.,Finer-Moore, J.,Stroud, R.M. (deposition date: 1992-09-16, release date: 1994-01-31, Last modification date: 2024-06-05) |
Primary citation | Kamb, A.,Finer-Moore, J.,Calvert, A.H.,Stroud, R.M. Structural basis for recognition of polyglutamyl folates by thymidylate synthase. Biochemistry, 31:9883-9890, 1992 Cited by PubMed: 1390771DOI: 10.1021/bi00156a005 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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