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2BAK

p38alpha MAP kinase bound to MPAQ

Summary for 2BAK
Entry DOI10.2210/pdb2bak/pdb
Related2BAJ 2BAL 2BAQ
DescriptorMitogen-activated protein kinase 14, N-(3-{[7-METHOXY-6-(2-PYRROLIDIN-1-YLETHOXY)QUINAZOLIN-4-YL]AMINO}-4-METHYLPHENYL)-2-MORPHOLIN-4-YLISONICOTINAMIDE (3 entities in total)
Functional Keywordsp38 map kinase, serine/threonine kinase, transferase
Biological sourceHomo sapiens (human)
Cellular locationCytoplasm (By similarity): Q16539
Total number of polymer chains1
Total formula weight42624.56
Authors
Gerhardt, S.,Breed, J.,Pauptit, R.A.,Read, J.,Norman, R.A.,Ward, W.H. (deposition date: 2005-10-14, release date: 2005-12-06, Last modification date: 2024-02-14)
Primary citationSullivan, J.E.,Holdgate, G.A.,Campbell, D.,Timms, D.,Gerhardt, S.,Breed, J.,Breeze, A.L.,Bermingham, A.,Pauptit, R.A.,Norman, R.A.,Embrey, K.J.,Read, J.,Vanscyoc, W.S.,Ward, W.H.
Prevention of MKK6-Dependent Activation by Binding to p38alpha MAP Kinase
Biochemistry, 44:16475-16490, 2005
Cited by
PubMed: 16342939
DOI: 10.1021/bi051714v
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.2 Å)
Structure validation

217705

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