2B9S
Crystal Structure of heterodimeric L. donovani topoisomerase I-vanadate-DNA complex
Summary for 2B9S
Entry DOI | 10.2210/pdb2b9s/pdb |
Descriptor | 5'-D(*AP*AP*AP*AP*AP*GP*AP*CP*TP*T)-3', 5'-D(*AP*GP*AP*AP*AP*AP*AP*TP*TP*TP*TP*T)-3', 5'-D(*AP*AP*AP*AP*AP*TP*TP*TP*TP*TP*CP*TP*AP*AP*GP*TP*CP*TP*TP*TP*TP*T)-3', ... (7 entities in total) |
Functional Keywords | topoisomerase i, vanadate complex, isomerase-dna complex, isomerase/dna |
Biological source | Leishmania donovani More |
Total number of polymer chains | 5 |
Total formula weight | 71607.03 |
Authors | Davies, D.R.,Hol, W.G.J. (deposition date: 2005-10-12, release date: 2006-01-17, Last modification date: 2024-02-14) |
Primary citation | Davies, D.R.,Mushtaq, A.,Interthal, H.,Champoux, J.J.,Hol, W.G. The Structure of the Transition State of the Heterodimeric Topoisomerase I of Leishmania donovani as a Vanadate Complex with Nicked DNA. J.Mol.Biol., 357:1202-1210, 2006 Cited by PubMed: 16487540DOI: 10.1016/j.jmb.2006.01.022 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.27 Å) |
Structure validation
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