2B7F

Crystal structure of human T-cell leukemia virus protease, a novel target for anti-cancer design

Summary for 2B7F

Entry DOI	10.2210/pdb2b7f/pdb
Related PRD ID	PRD_000429
Descriptor	HTLV protease, (ACE)APQV(STA)VMHP peptide, PHOSPHATE ION, ... (4 entities in total)
Functional Keywords	hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological source	Human T-lymphotropic virus 1
Cellular location	Matrix protein p19: Virion . Capsid protein p24: Virion . Nucleocapsid protein p15-pro: Virion : P10274
Total number of polymer chains	9
Total formula weight	78776.32
Authors	Li, M.,Laco, G.S.,Jaskolski, M.,Rozycki, J.,Alexandratos, J.,Wlodawer, A.,Gustchina, A. (deposition date: 2005-10-04, release date: 2005-12-06, Last modification date: 2023-11-15)
Primary citation	Li, M.,Laco, G.S.,Jaskolski, M.,Rozycki, J.,Alexandratos, J.,Wlodawer, A.,Gustchina, A. Crystal structure of human T cell leukemia virus protease, a novel target for anticancer drug design Proc.Natl.Acad.Sci.Usa, 102:18332-18337, 2005 Cited by PubMed: 16352712 DOI: 10.1073/pnas.0509335102 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.6 Å)

Structure validation