2B53
Human cyclin dependent kinase 2 (CDK2) complexed with DIN-234325
Summary for 2B53
Entry DOI | 10.2210/pdb2b53/pdb |
Related | 2B52 2B54 2B55 |
Descriptor | Cell division protein kinase 2, 6-(3-AMINOPHENYL)-N-(TERT-BUTYL)-2-(TRIFLUOROMETHYL)QUINAZOLIN-4-AMINE (3 entities in total) |
Functional Keywords | protein kinase, cell cycle, phosphorylation, cell division, mitosis, inhibition, transferase |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 1 |
Total formula weight | 34336.86 |
Authors | Muckelbauer, J. (deposition date: 2005-09-27, release date: 2005-10-11, Last modification date: 2024-02-14) |
Primary citation | Sielecki, T.M.,Johnson, T.L.,Liu, J.,Muckelbauer, J.K.,Grafstrom, R.H.,Cox, S.,Boylan, J.,Burton, C.R.,Chen, H.,Smallwood, A.,Chang, C.-H.,Boisclair, M.,Benfield, P.A.,Trainor, G.L.,Seitz, S.P. Quinazolines as Cyclin Dependent Kinase Inhibitors Bioorg.Med.Chem.Lett., 11:1157-1160, 2001 Cited by PubMed: 11354366DOI: 10.1016/S0960-894X(01)00185-8 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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