2B1V
Human estrogen receptor alpha ligand-binding domain in complex with OBCP-1M and a glucocorticoid receptor interacting protein 1 NR box II peptide
Summary for 2B1V
Entry DOI | 10.2210/pdb2b1v/pdb |
Related | 1ZKY 2B1V 2B1Z |
Descriptor | Estrogen receptor, Nuclear receptor coactivator 2, 4-[(1S,2S,5S)-5-(HYDROXYMETHYL)-8-METHYL-3-OXABICYCLO[3.3.1]NON-7-EN-2-YL]PHENOL, ... (4 entities in total) |
Functional Keywords | estrogen receptor, lbd, grip peptide, hormone-growth factor receptor complex, hormone/growth factor receptor |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 4 |
Total formula weight | 62736.16 |
Authors | Rajan, S.S.,Hsieh, R.W.,Sharma, S.K.,Greene, G.L. (deposition date: 2005-09-16, release date: 2006-05-09, Last modification date: 2023-08-23) |
Primary citation | Hsieh, R.W.,Rajan, S.S.,Sharma, S.K.,Guo, Y.,Desombre, E.R.,Mrksich, M.,Greene, G.L. Identification of ligands with bicyclic scaffolds provides insights into mechanisms of estrogen receptor subtype selectivity. J.Biol.Chem., 281:17909-17919, 2006 Cited by PubMed: 16648639DOI: 10.1074/jbc.M513684200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
Download full validation report