2B0U

The Structure of the Follistatin:Activin Complex

Summary for 2B0U

• Entry DOI: 10.2210/pdb2b0u/pdb
• Descriptor: Inhibin beta A chain, Follistatin, IRIDIUM (III) ION, ... (6 entities in total)
• Functional Keywords: activin, follistatin, tgf-beta, morphogen, inhibin, signaling protein
• Biological source: Homo sapiens (human); More
• Cellular location: Secreted: P08476 P19883
• Total number of polymer chains: 4
• Total formula weight: 90655.58

Authors

Thompson, T.B.,Lerch, T.F.,Cook, R.W.,Woodruff, T.K.,Jardetzky, T.S. (deposition date: 2005-09-14, release date: 2005-10-11, Last modification date: 2017-10-11)

• Primary citation: Thompson, T.B.,Lerch, T.F.,Cook, R.W.,Woodruff, T.K.,Jardetzky, T.S.; The Structure of the Follistatin:Activin Complex Reveals Antagonism of Both Type I and Type II Receptor Binding.; Dev.Cell, 9:535-543, 2005; PubMed: 16198295; DOI: 10.1016/j.devcel.2005.09.008

Experimental method

X-RAY DIFFRACTION (2.8 Å)