2AYB

Crystal structure of HPV6a E2 DNA Binding Domain bound to a 16 base pair DNA target

Summary for 2AYB

• Entry DOI: 10.2210/pdb2ayb/pdb
• Related: 2AYE 2AYG
• Descriptor: 5'-D(*CP*AP*AP*CP*CP*GP*AP*AP*TP*TP*CP*GP*GP*TP*TP*G)-3', Regulatory protein E2 (3 entities in total)
• Functional Keywords: protein-dna complex, double helix, beta barrel, transcription-dna complex, transcription/dna
• Biological source: Human papillomavirus type 6a
• Cellular location: Host nucleus : Q84294
• Total number of polymer chains: 4
• Total formula weight: 30278.09

Authors

Hooley, E.,Brady, R.L.,Gaston, K. (deposition date: 2005-09-07, release date: 2006-08-22, Last modification date: 2023-08-23)

• Primary citation: Hooley, E.,Fairweather, V.,Clarke, A.R.,Gaston, K.,Brady, R.L.; The recognition of local DNA conformation by the human papillomavirus type 6 E2 protein.; Nucleic Acids Res., 34:3897-3908, 2006; PubMed: 16914454; DOI: 10.1093/nar/gkl466

Experimental method

X-RAY DIFFRACTION (3.2 Å)