2ATI
Glycogen Phosphorylase Inhibitors
Summary for 2ATI
Entry DOI | 10.2210/pdb2ati/pdb |
Related | 1WUT 1WUY 1WV0 1WV1 |
Descriptor | Glycogen phosphorylase, liver form, alpha-D-glucopyranose, N-(2-CHLORO-4-FLUOROBENZOYL)-N'-(5-HYDROXY-2-METHOXYPHENYL)UREA, ... (5 entities in total) |
Functional Keywords | glycogen phosphorylase, transferase |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 2 |
Total formula weight | 195822.56 |
Authors | Klabunde, T.,Wendt, K.U.,Kadereit, D.,Brachvogel, V.,Burger, H.J.,Herling, A.W.,Oikonomakos, N.G.,Schmoll, D.,Sarubbi, E.,von Roedern, E.,Schoenafinger, K.,Defossa, E. (deposition date: 2005-08-25, release date: 2006-08-25, Last modification date: 2020-07-29) |
Primary citation | Klabunde, T.,Wendt, K.U.,Kadereit, D.,Brachvogel, V.,Burger, H.J.,Herling, A.W.,Oikonomakos, N.G.,Kosmopoulou, M.N.,Schmoll, D.,Sarubbi, E.,von Roedern, E.,Defossa, E. Acyl ureas as human liver glycogen phosphorylase inhibitors for the treatment of type 2 diabetes. J.Med.Chem., 48:6178-6193, 2005 Cited by PubMed: 16190745DOI: 10.1021/jm049034y PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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