2AMQ
Crystal Structure Of SARS_CoV Mpro in Complex with an Inhibitor N3
Summary for 2AMQ
Entry DOI | 10.2210/pdb2amq/pdb |
Related | 1UJ1 2AMD 2AMP |
Related PRD ID | PRD_002214 |
Descriptor | 3C-like proteinase, N-[(5-METHYLISOXAZOL-3-YL)CARBONYL]ALANYL-L-VALYL-N~1~-((1R,2Z)-4-(BENZYLOXY)-4-OXO-1-{[(3R)-2-OXOPYRROLIDIN-3-YL]METHYL}BUT-2-ENYL)-L-LEUCINAMIDE (3 entities in total) |
Functional Keywords | anti-parallel b-barrel, anti-parallel a-helices, hydrolase |
Biological source | SARS coronavirus More |
Total number of polymer chains | 4 |
Total formula weight | 69937.75 |
Authors | |
Primary citation | Yang, H.,Xie, W.,Xue, X.,Yang, K.,Ma, J.,Liang, W.,Zhao, Q.,Zhou, Z.,Pei, D.,Ziebuhr, J.,Hilgenfeld, R.,Yuen, K.Y.,Wong, L.,Gao, G.,Chen, S.,Chen, Z.,Ma, D.,Bartlam, M.,Rao, Z. Design of Wide-Spectrum Inhibitors Targeting Coronavirus Main Proteases. Plos Biol., 3:324-334, 2005 Cited by PubMed: 16128623DOI: 10.1371/journal.pbio.0030324 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
Download full validation report