2AKM
Fluoride Inhibition of Enolase: Crystal Structure of the Inhibitory Complex
Summary for 2AKM
Entry DOI | 10.2210/pdb2akm/pdb |
Related | 1TE6 2AKZ |
Descriptor | Gamma enolase, MAGNESIUM ION, PHOSPHATE ION, ... (5 entities in total) |
Functional Keywords | enolase; fluoride inhibition; negative cooperativity; glycolysis; crystal structure; isothermal titration calorimetry, lyase |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm (By similarity): P09104 |
Total number of polymer chains | 2 |
Total formula weight | 96421.16 |
Authors | Qin, J.,Chai, G.,Brewer, J.M.,Lovelace, L.L. (deposition date: 2005-08-03, release date: 2006-03-21, Last modification date: 2023-08-23) |
Primary citation | Qin, J.,Chai, G.,Brewer, J.M.,Lovelace, L.L.,Lebioda, L. Fluoride inhibition of enolase: crystal structure and thermodynamics Biochemistry, 45:793-800, 2006 Cited by PubMed: 16411755DOI: 10.1021/bi051558s PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.92 Å) |
Structure validation
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