2AH2
Trypanosoma cruzi trans-sialidase in complex with 2,3-difluorosialic acid (covalent intermediate)
Replaces: 1S0KSummary for 2AH2
Entry DOI | 10.2210/pdb2ah2/pdb |
Related | 2A75 2AGS |
Descriptor | trans-sialidase, CHLORIDE ION, 5-acetamido-3,5-dideoxy-3-fluoro-D-erythro-alpha-L-manno-non-2-ulopyranosonic acid, ... (6 entities in total) |
Functional Keywords | transglycosidase, covalent intermediate, trypanosoma cruzi, sialic acid, hydrolase |
Biological source | Trypanosoma cruzi |
Total number of polymer chains | 1 |
Total formula weight | 72088.35 |
Authors | Amaya, M.F.,Watts, A.G.,Damager, I.,Wehenkel, A.,Nguyen, T.,Buschiazzo, A.,Paris, G.,Frasch, A.C.,Withers, S.G.,Alzari, P.M. (deposition date: 2005-07-27, release date: 2005-08-23, Last modification date: 2021-10-20) |
Primary citation | Amaya, M.F.,Watts, A.G.,Damager, I.,Wehenkel, A.,Nguyen, T.,Buschiazzo, A.,Paris, G.,Frasch, A.C.,Withers, S.G.,Alzari, P.M. Structural Insights into the Catalytic Mechanism of Trypanosoma cruzi trans-Sialidase Structure, 12:775-784, 2004 Cited by PubMed: 15130470DOI: 10.1016/j.str.2004.02.036 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.6 Å) |
Structure validation
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