2AG5

Crystal Structure of Human DHRS6

Summary for 2AG5

Entry DOI	10.2210/pdb2ag5/pdb
Descriptor	dehydrogenase/reductase (SDR family) member 6, SULFATE ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... (4 entities in total)
Functional Keywords	protein-co-factor complex, structural genomics, structural genomics consortium, sgc, oxidoreductase
Biological source	Homo sapiens (human)
Cellular location	Cytoplasm: Q9BUT1
Total number of polymer chains	4
Total formula weight	110281.30
Authors	Kunde, G.,Lukacik, P.,Papagrigoriou, E.,Sundstrom, M.,Arrowsmith, C.,Weigelt, J.,Edwards, A.,Von Delft, F.,Oppermann, U.,Structural Genomics Consortium (SGC) (deposition date: 2005-07-26, release date: 2005-08-09, Last modification date: 2024-03-13)
Primary citation	Guo, K.,Lukacik, P.,Papagrigoriou, E.,Meier, M.,Lee, W.H.,Adamski, J.,Oppermann, U. Characterization of human DHRS6, an orphan short chain dehydrogenase/reductase enzyme: a novel, cytosolic type 2 R-beta-hydroxybutyrate dehydrogenase J.Biol.Chem., 281:10291-10297, 2006 Cited by PubMed: 16380372 DOI: 10.1074/jbc.M511346200 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.84 Å)

Structure validation