Summary for 2ACE
Entry DOI | 10.2210/pdb2ace/pdb |
Descriptor | ACETYLCHOLINESTERASE, ACETYLCHOLINE (3 entities in total) |
Functional Keywords | serine hydrolase, neurotransmitter cleavage, catalytic triad, alpha/beta hydrolase |
Biological source | Torpedo californica (Pacific electric ray) |
Cellular location | Isoform H: Cell membrane; Lipid-anchor, GPI- anchor. Isoform T: Cell membrane; Peripheral membrane protein: P04058 |
Total number of polymer chains | 1 |
Total formula weight | 60882.72 |
Authors | Harel, M.,Raves, M.L.,Silman, I.,Sussman, J.L. (deposition date: 1996-06-23, release date: 1996-11-08, Last modification date: 2023-08-09) |
Primary citation | Raves, M.L.,Harel, M.,Pang, Y.-P.,Silman, I.,Kozikowski, A.P.,Sussman, J.L. Structure of acetylcholinesterase complexed with the nootropic alkaloid, (-)-huperzine A. Nat.Struct.Biol., 4:57-63, 1997 Cited by PubMed: 8989325DOI: 10.1038/nsb0197-57 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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