2AC5
Structure of human Mnk2 Kinase Domain mutant D228G
Summary for 2AC5
Entry DOI | 10.2210/pdb2ac5/pdb |
Related | 2AC3 |
Descriptor | MAP kinase-interacting serine/threonine kinase 2, ZINC ION (3 entities in total) |
Functional Keywords | dfg motif, transferase |
Biological source | Homo sapiens (human) |
Cellular location | Isoform 2: Nucleus, PML body. Isoform 1: Cytoplasm: Q9HBH9 |
Total number of polymer chains | 1 |
Total formula weight | 35669.87 |
Authors | Jauch, R.,Wahl, M.C.,Jakel, S.,Schreiter, K.,Aicher, B.,Jackle, H. (deposition date: 2005-07-18, release date: 2005-10-04, Last modification date: 2024-05-29) |
Primary citation | Jauch, R.,Jakel, S.,Netter, C.,Schreiter, K.,Aicher, B.,Jackle, H.,Wahl, M.C. Crystal structures of the Mnk2 kinase domain reveal an inhibitory conformation and a zinc binding site. Structure, 13:1559-1568, 2005 Cited by PubMed: 16216586DOI: 10.1016/j.str.2005.07.013 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.2 Å) |
Structure validation
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