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2AC5

Structure of human Mnk2 Kinase Domain mutant D228G

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
MAP kinase-interacting serine/threonine kinase 2polymer31635604.51UniProt (Q9HBH9)
Pfam (PF00069)
Homo sapiens (human)MAP kinase signal-integrating kinase 2, Mnk2
2B
(A)
ZINC IONnon-polymer65.41Chemie (ZN)
3C
(A)
waterwater18.018Chemie (HOH)
Sequence modifications
A: 72 - 385 (UniProt: Q9HBH9)
PDBExternal DatabaseDetails
Gly 70-expression tag
Ser 71-expression tag
Gly 228Asp 181engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight35604.5
Non-Polymers*Number of molecules1
Total formula weight65.4
All*Total formula weight35669.9
*Water molecules are not included.

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PDB entries from 2025-08-06

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