2A91

Crystal structure of ErbB2 domains 1-3

2A91 の概要

• エントリーDOI: 10.2210/pdb2a91/pdb
• 分子名称: Receptor tyrosine-protein kinase erbB-2, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total)
• 機能のキーワード: tyrosine kinase receptor; cell-surface receptor, signaling protein, transferase, membrane protein
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 57860.27

構造登録者

Garrett, T.P.J.,McKern, N.M.,Lou, M.,Elleman, T.C.,Adams, T.E.,Lovrecz, G.O.,Kofler, M.,Jorissen, R.N.,Nice, E.C.,Burgess, A.W. (登録日: 2005-07-11, 公開日: 2005-07-26, 最終更新日: 2022-12-21)

• 主引用文献: Garrett, T.P.J.,McKern, N.M.,Lou, M.,Elleman, T.C.,Adams, T.E.,Lovrecz, G.O.,Kofler, M.,Jorissen, R.N.,Nice, E.C.,Burgess, A.W.; The Crystal Structure of a Truncated ErbB2 Ectodomain Reveals an Active Conformation, Poised to Interact with Other ErbB Receptors; Mol.Cell, 11:495-505, 2003; PubMed: 12620236; DOI: 10.1016/S1097-2765(03)00048-0

実験手法

X-RAY DIFFRACTION (2.5 Å)