2A8B
Crystal Structure of the Catalytic Domain of Human Tyrosine Phosphatase Receptor, Type R
Replaces: 1ZEPSummary for 2A8B
Entry DOI | 10.2210/pdb2a8b/pdb |
Related | 1JLN |
Descriptor | Receptor-type tyrosine-protein phosphatase R, CHLORIDE ION (3 entities in total) |
Functional Keywords | protein tyrosine phosphatase, receptor, human, structural genomics, structural genomics consortium, sgc, hydrolase |
Biological source | Homo sapiens (human) |
Cellular location | Isoform Alpha: Cell membrane; Single-pass type I membrane protein. Isoform Delta: Cytoplasm, perinuclear region. Isoform Gamma: Cytoplasm, perinuclear region: Q15256 |
Total number of polymer chains | 1 |
Total formula weight | 32319.49 |
Authors | Ugochukwu, E.,Eswaran, J.,Barr, A.,Longman, E.,Arrowsmith, C.,Edwards, A.,Sundstrom, M.,von Delft, F.,Knapp, S.,Structural Genomics Consortium (SGC) (deposition date: 2005-07-07, release date: 2005-07-19, Last modification date: 2023-08-23) |
Primary citation | Eswaran, J.,von Kries, J.P.,Marsden, B.,Longman, E.,Debreczeni, J.E.,Ugochukwu, E.,Turnbull, A.,Lee, W.H.,Knapp, S.,Barr, A.J. Crystal structures and inhibitor identification for PTPN5, PTPRR and PTPN7: a family of human MAPK-specific protein tyrosine phosphatases. Biochem.J., 395:483-491, 2006 Cited by PubMed: 16441242DOI: 10.1042/BJ20051931 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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