2A1X
Human phytanoyl-coa 2-hydroxylase in complex with iron and 2-oxoglutarate
Summary for 2A1X
Entry DOI | 10.2210/pdb2a1x/pdb |
Descriptor | Phytanoyl-CoA dioxygenase, FE (II) ION, 2-OXOGLUTARIC ACID, ... (4 entities in total) |
Functional Keywords | beta jelly roll, double-stranded beta-helix, structural genomics, structural genomics consortium, sgc, oxidoreductase |
Biological source | Homo sapiens (human) |
Cellular location | Peroxisome: O14832 |
Total number of polymer chains | 1 |
Total formula weight | 35692.61 |
Authors | Kavanagh, K.L.,McDonough, M.A.,Searles, T.,Butler, D.,Bunkoczi, G.,von Delft, F.,Edwards, A.,Arrowsmith, C.,Sundstrom, M.,Schofield, C.J.,Oppermann, U.,Structural Genomics Consortium (SGC) (deposition date: 2005-06-21, release date: 2005-08-16, Last modification date: 2024-02-14) |
Primary citation | McDonough, M.A.,Kavanagh, K.L.,Butler, D.,Searles, T.,Oppermann, U.,Schofield, C.J. Structure of Human Phytanoyl-CoA 2-Hydroxylase Identifies Molecular Mechanisms of Refsum Disease J.Biol.Chem., 280:41101-41110, 2005 Cited by PubMed: 16186124DOI: 10.1074/jbc.M507528200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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