2A1X

Human phytanoyl-coa 2-hydroxylase in complex with iron and 2-oxoglutarate

2A1X の概要

• エントリーDOI: 10.2210/pdb2a1x/pdb
• 分子名称: Phytanoyl-CoA dioxygenase, FE (II) ION, 2-OXOGLUTARIC ACID, ... (4 entities in total)
• 機能のキーワード: beta jelly roll, double-stranded beta-helix, structural genomics, structural genomics consortium, sgc, oxidoreductase
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Peroxisome: O14832
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 35692.61

構造登録者

Kavanagh, K.L.,McDonough, M.A.,Searles, T.,Butler, D.,Bunkoczi, G.,von Delft, F.,Edwards, A.,Arrowsmith, C.,Sundstrom, M.,Schofield, C.J.,Oppermann, U.,Structural Genomics Consortium (SGC) (登録日: 2005-06-21, 公開日: 2005-08-16, 最終更新日: 2024-02-14)

• 主引用文献: McDonough, M.A.,Kavanagh, K.L.,Butler, D.,Searles, T.,Oppermann, U.,Schofield, C.J.; Structure of Human Phytanoyl-CoA 2-Hydroxylase Identifies Molecular Mechanisms of Refsum Disease; J.Biol.Chem., 280:41101-41110, 2005; PubMed: 16186124; DOI: 10.1074/jbc.M507528200

実験手法

X-RAY DIFFRACTION (2.5 Å)