2ZPP
Neutron crystal structure of cubic insulin at pD9
Summary for 2ZPP
Entry DOI | 10.2210/pdb2zpp/pdb |
Related | 2EFA |
Descriptor | Insulin A chain, Insulin B chain (3 entities in total) |
Functional Keywords | hormone, cubic, porcine insulin, carbohydrate metabolism, cleavage on pair of basic residues, glucose metabolism, secreted |
Biological source | Sus scrofa (Pig) More |
Cellular location | Secreted: P01315 P01315 |
Total number of polymer chains | 2 |
Total formula weight | 5787.63 |
Authors | Ishikawa, T.,Tanaka, I.,Niimura, N. (deposition date: 2008-07-26, release date: 2008-10-28, Last modification date: 2023-11-01) |
Primary citation | Ishikawa, T.,Chatake, T.,Morimoto, Y.,Maeda, M.,Kurihara, K.,Tanaka, I.,Niimura, N. An abnormal pK(a) value of internal histidine of the insulin molecule revealed by neutron crystallographic analysis Biochem.Biophys.Res.Commun., 376:32-35, 2008 Cited by PubMed: 18725203DOI: 10.1016/j.bbrc.2008.08.071 PDB entries with the same primary citation |
Experimental method | NEUTRON DIFFRACTION (2.5 Å) |
Structure validation
Download full validation report