2ZFR
Exploring thrombin S3 pocket
Summary for 2ZFR
Entry DOI | 10.2210/pdb2zfr/pdb |
Related | 2ZDA 2ZDM 3BIU 3BIV |
Related PRD ID | PRD_000605 |
Descriptor | thrombin light chain, thrombin heavy chain, Hirudin, ... (7 entities in total) |
Functional Keywords | blood clotting/hydrolase inhibitors, acute phase, cleavage on pair of basic residues, disease mutation, gamma-carboxyglutamic acid, glycoprotein, kringle, protease, secreted, serine protease, zymogen, protease inhibitor, serine protease inhibitor, sulfation, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Homo sapiens (Human) More |
Cellular location | Secreted, extracellular space: P00734 P00734 Secreted: P09945 |
Total number of polymer chains | 3 |
Total formula weight | 35935.87 |
Authors | Brandt, T.,Baum, B.,Heine, A.,Klebe, G. (deposition date: 2008-01-10, release date: 2009-01-13, Last modification date: 2023-11-15) |
Primary citation | Brandt, T.,Baum, B.,Hangauer, D.,Heine, A.,Klebe, G. Exploring thrombin S3 pocket To be Published, |
Experimental method | X-RAY DIFFRACTION (1.85 Å) |
Structure validation
Download full validation report