2ZFF

Exploring Thrombin S1-pocket

Summary for 2ZFF

• Entry DOI: 10.2210/pdb2zff/pdb
• Related: 1H8D 1YPG 2ZC9 2ZDA 2ZDV 2ZF0 2ZFP
• Related PRD ID: PRD_000609
• Descriptor: Thrombin light chain, Thrombin heavy chain, Hirudin variant-1, ... (6 entities in total)
• Functional Keywords: blood clotting/hydrolase inhibitors, acute phase, blood coagulation, cleavage on pair of basic residues, disease mutation, gamma-carboxyglutamic acid, glycoprotein, kringle, protease, secreted, serine protease, zymogen, blood clotting-hydrolase inhibitor complex, blood clotting/hydrolase inhibitor
• Biological source: Homo sapiens (human); More
• Cellular location: Secreted, extracellular space: P00734 P00734; Secreted: P01050
• Total number of polymer chains: 3
• Total formula weight: 35694.63

Authors

Baum, B.,Heine, A.,Klebe, G. (deposition date: 2008-01-04, release date: 2008-12-16, Last modification date: 2023-11-15)

• Primary citation: Baum, B.,Hangauer, D.,Heine, A.,Klebe, G.; Exploring Thrombin S1-pocket; To be Published,

Experimental method

X-RAY DIFFRACTION (1.47 Å)