2Z5U
Crystal structure of Lysine-specific histone demethylase 1
Summary for 2Z5U
| Entry DOI | 10.2210/pdb2z5u/pdb |
| Related | 2EJR 2Z3Y |
| Descriptor | Lysine-specific histone demethylase 1, FAD-trans-2-Phenylcyclopropylamine Adduct (3 entities in total) |
| Functional Keywords | chromatin, histone demethylase, nucleosome, transcription, lsd1, lysine-specific, chromatin regulator, fad, nucleus, oxidoreductase, phosphorylation, repressor, transcription regulation, structural genomics, nppsfa, national project on protein structural and functional analyses, riken structural genomics/proteomics initiative, rsgi |
| Biological source | Homo sapiens (human) |
| Total number of polymer chains | 1 |
| Total formula weight | 74571.97 |
| Authors | Mimasu, S.,Sengoku, T.,Yokoyama, S.,RIKEN Structural Genomics/Proteomics Initiative (RSGI) (deposition date: 2007-07-17, release date: 2008-04-01, Last modification date: 2023-11-01) |
| Primary citation | Mimasu, S.,Sengoku, T.,Fukuzawa, S.,Umehara, T.,Yokoyama, S. Crystal structure of histone demethylase LSD1 and tranylcypromine at 2.25 A Biochem.Biophys.Res.Commun., 366:15-22, 2008 Cited by PubMed: 18039463DOI: 10.1016/j.bbrc.2007.11.066 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.25 Å) |
Structure validation
Download full validation report
