2Z5U
Crystal structure of Lysine-specific histone demethylase 1
Functional Information from GO Data
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 38 |
Details | BINDING SITE FOR RESIDUE FAJ A 1 |
Chain | Residue |
A | ILE284 |
A | GLY314 |
A | GLY315 |
A | ARG316 |
A | LEU329 |
A | GLY330 |
A | ALA331 |
A | MET332 |
A | VAL333 |
A | THR335 |
A | THR588 |
A | GLY285 |
A | VAL590 |
A | THR624 |
A | LEU625 |
A | PRO626 |
A | VAL637 |
A | TRP751 |
A | TRP756 |
A | TYR761 |
A | GLY800 |
A | GLU801 |
A | GLY287 |
A | ALA809 |
A | THR810 |
A | VAL811 |
A | ALA814 |
A | HOH839 |
A | HOH847 |
A | HOH891 |
A | HOH892 |
A | HOH916 |
A | VAL288 |
A | SER289 |
A | LEU307 |
A | GLU308 |
A | ALA309 |
A | ARG310 |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 7 |
Details | BINDING: BINDING => ECO:0000269|PubMed:16885027, ECO:0000269|PubMed:16956976, ECO:0000269|PubMed:21300290, ECO:0000269|PubMed:23721412, ECO:0007744|PDB:2DW4, ECO:0007744|PDB:2H94, ECO:0007744|PDB:2HKO, ECO:0007744|PDB:2IW5, ECO:0007744|PDB:2V1D, ECO:0007744|PDB:2X0L, ECO:0007744|PDB:2XAF, ECO:0007744|PDB:2XAG, ECO:0007744|PDB:2XAH, ECO:0007744|PDB:2XAJ, ECO:0007744|PDB:2XAQ, ECO:0007744|PDB:2XAS, ECO:0007744|PDB:2Y48, ECO:0007744|PDB:3ZMS, ECO:0007744|PDB:3ZMT, ECO:0007744|PDB:3ZMU, ECO:0007744|PDB:3ZMV, ECO:0007744|PDB:3ZMZ, ECO:0007744|PDB:3ZN0, ECO:0007744|PDB:3ZN1 |
Chain | Residue | Details |
A | SER289 | |
A | GLU308 | |
A | ARG310 | |
A | ARG316 | |
A | MET332 | |
A | GLU801 | |
A | THR810 |
site_id | SWS_FT_FI2 |
Number of Residues | 3 |
Details | MOD_RES: N6-acetyllysine => ECO:0000269|PubMed:27292636 |
Chain | Residue | Details |
A | LYS432 | |
A | LYS433 | |
A | LYS436 |
site_id | SWS_FT_FI3 |
Number of Residues | 1 |
Details | MOD_RES: Phosphoserine => ECO:0007744|PubMed:23186163 |
Chain | Residue | Details |
A | SER611 |
site_id | SWS_FT_FI4 |
Number of Residues | 2 |
Details | CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) => ECO:0007744|PubMed:28112733 |
Chain | Residue | Details |
A | LYS442 | |
A | LYS469 |
site_id | SWS_FT_FI5 |
Number of Residues | 2 |
Details | CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000305|PubMed:25018020 |
Chain | Residue | Details |
A | LYS503 |
Catalytic Information from CSA
site_id | CSA1 |
Number of Residues | 1 |
Details | Annotated By Reference To The Literature 1f8r |
Chain | Residue | Details |
A | THR335 |
site_id | CSA2 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1f8r |
Chain | Residue | Details |
A | LYS661 | |
A | HIS551 |