2YLM

Mechanism of USP7 (HAUSP) activation by its C-terminal ubiquitin-like domain (HUBL) and allosteric regulation by GMP-synthetase.

Summary for 2YLM

Entry DOI	10.2210/pdb2ylm/pdb
Related	1NB8 1NBF 2F1W 2F1X 2F1Y 2F1Z 2FOJ 2FOO 2FOP 2XXN
Descriptor	UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 7, CHLORIDE ION (3 entities in total)
Functional Keywords	hydrolase, ubl
Biological source	HOMO SAPIENS (HUMAN)
Cellular location	Nucleus: Q93009
Total number of polymer chains	1
Total formula weight	61964.89
Authors	Faesen, A.C.,Perrakis, A.,Sixma, T.K. (deposition date: 2011-06-03, release date: 2011-10-19, Last modification date: 2014-01-15)
Primary citation	Faesen, A.C.,Dirac, A.M.G.,Shanmugham, A.,Ovaa, H.,Perrakis, A.,Sixma, T.K. Mechanism of Usp7/Hausp Activation by its C- Terminal Ubiquitin-Like Domain and Allosteric Regulation by Gmp-Synthetase Mol.Cell, 44:147-, 2011 Cited by PubMed: 21981925 DOI: 10.1016/J.MOLCEL.2011.06.034 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.7 Å)

Structure validation