2YLM
Mechanism of USP7 (HAUSP) activation by its C-terminal ubiquitin-like domain (HUBL) and allosteric regulation by GMP-synthetase.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 7 | polymer | 530 | 61929.4 | 1 | UniProt (Q93009) Pfam (PF12436) Pfam (PF14533) In PDB | HOMO SAPIENS (HUMAN) | UBIQUITIN SPECIFIC PROTEASE 7, DEUBIQUITINATING ENZYME 7, HERPESVIRUS-ASSOCIATED UBIQUITIN-SPECIFIC PROTEASE, UBIQUITIN THIOESTERASE 7, UBIQUITIN-SPECIFIC-PROCESSING PROTEASE 7 |
| 2 | A | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 3 | water | water | 18.0 | 128 | Chemie (HOH) |
Sequence modifications
A: 560 - 1084 (UniProt: Q93009)
| PDB | External Database | Details |
|---|---|---|
| Gly 555 | - | expression tag |
| Pro 556 | - | expression tag |
| Leu 557 | - | expression tag |
| Gly 558 | - | expression tag |
| Ser 559 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 61929.4 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 35.5 | |
| All* | Total formula weight | 61964.9 |
