2YH1
Model of human U2AF65 tandem RRM1 and RRM2 domains with eight-site uridine binding
Summary for 2YH1
Entry DOI | 10.2210/pdb2yh1/pdb |
Related | 1JMT 1O0P 1OPI 1U2F 2G4B 2U2F 2YH0 2YH4 |
NMR Information | BMRB: 17623 |
Descriptor | SPLICING FACTOR U2AF 65 KDA SUBUNIT, 5'-R(*UP*UP*UP*UP*UP*UP*UP*UP*UP)-3' (2 entities in total) |
Functional Keywords | transcription, pre-mrna splicing |
Biological source | HOMO SAPIENS (HUMAN) More |
Total number of polymer chains | 2 |
Total formula weight | 24221.06 |
Authors | Mackereth, C.D.,Madl, T.,Simon, B.,Zanier, K.,Gasch, A.,Sattler, M. (deposition date: 2011-04-26, release date: 2011-07-20, Last modification date: 2024-05-15) |
Primary citation | Mackereth, C.D.,Madl, T.,Bonnal, S.,Simon, B.,Zanier, K.,Gasch, A.,Rybin, V.,Valcarcel, J.,Sattler, M. Multi-Domain Conformational Selection Underlies Pre-Mrna Splicing Regulation by U2Af Nature, 475:408-, 2011 Cited by PubMed: 21753750DOI: 10.1038/NATURE10171 PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
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