2YCT
Tyrosine phenol-lyase from Citrobacter freundii in complex with pyridine N-oxide and the quinonoid intermediate formed with L-alanine
Summary for 2YCT
Entry DOI | 10.2210/pdb2yct/pdb |
Related | 1TPL 2EZ1 2EZ2 2TPL 2VLF 2VLH 2YCN 2YCP 2YHK |
Descriptor | TYROSINE PHENOL-LYASE, PYRIDOXAL-5'-PHOSPHATE, (2E)-2-{[(Z)-{3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4(1H)-YLIDENE}METHYL]IMINO}PROPANOIC ACID, ... (8 entities in total) |
Functional Keywords | lyase, pyridoxal 5'-phosphate dependent enzyme, beta-elimination |
Biological source | CITROBACTER FREUNDII |
Total number of polymer chains | 2 |
Total formula weight | 104730.92 |
Authors | Milic, D.,Demidkina, T.V.,Faleev, N.G.,Phillips, R.S.,Matkovic-Calogovic, D.,Antson, A.A. (deposition date: 2011-03-16, release date: 2011-09-14, Last modification date: 2023-12-20) |
Primary citation | Milic, D.,Demidkina, T.V.,Faleev, N.G.,Phillips, R.S.,Matkovic-Calogovic, D.,Antson, A.A. Crystallographic Snapshots of Tyrosine Phenol-Lyase Show that Substrate Strain Plays a Role in C-C Bond Cleavage J.Am.Chem.Soc., 133:16468-, 2011 Cited by PubMed: 21899319DOI: 10.1021/JA203361G PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.25 Å) |
Structure validation
Download full validation report