2XR5
Crystal structure of the complex of the carbohydrate recognition domain of human DC-SIGN with pseudo dimannoside mimic.
Summary for 2XR5
| Entry DOI | 10.2210/pdb2xr5/pdb |
| Related | 1K9I 1SL4 1SL5 2B6B 2XR6 |
| Descriptor | CD209 ANTIGEN, alpha-D-mannopyranose, dimethyl (1S,2S,4S,5S)-4,5-dihydroxycyclohexane-1,2-dicarboxylate, ... (7 entities in total) |
| Functional Keywords | sugar binding protein |
| Biological source | HOMO SAPIENS (HUMAN) |
| Total number of polymer chains | 1 |
| Total formula weight | 19732.05 |
| Authors | Thepaut, M.,Suitkeviciute, I.,Sattin, S.,Reina, J.,Bernardi, A.,Fieschi, F. (deposition date: 2010-09-10, release date: 2011-10-19, Last modification date: 2023-12-20) |
| Primary citation | Thepaut, M.,Guzzi, C.,Sutkeviciute, I.,Sattin, S.,Ribeiro-Viana, R.,Varga, N.,Chabrol, E.,Rojo, J.,Bernardi, A.,Angulo, J.,Nieto, P.M.,Fieschi, F. Structure of a Glycomimetic Ligand in the Carbohydrate Recognition Domain of C-Type Lectin Dc-Sign. Structural Requirements for Selectivity and Ligand Design. J.Am.Chem.Soc., 135:2518-, 2013 Cited by PubMed: 23360500DOI: 10.1021/JA3053305 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.42 Å) |
Structure validation
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