2X0Y
Screening-based discovery of drug-like O-GlcNAcase inhibitor scaffolds
Summary for 2X0Y
Entry DOI | 10.2210/pdb2x0y/pdb |
Related | 2CBI 2CBJ 2J62 2JH2 2V5C 2V5D 2VUR 2WB5 |
Descriptor | O-GLCNACASE NAGJ, 7-[(2S)-2,3-DIHYDROXYPROPYL]-1,3-DIMETHYL-3,7-DIHYDRO-1H-PURINE-2,6-DIONE (3 entities in total) |
Functional Keywords | glycosidase, hydrolase, cell adhesion |
Biological source | CLOSTRIDIUM PERFRINGENS |
Total number of polymer chains | 2 |
Total formula weight | 133885.91 |
Authors | Dorfmueller, H.C.,van Aalten, D.M.F. (deposition date: 2009-12-18, release date: 2010-01-12, Last modification date: 2023-12-20) |
Primary citation | Dorfmueller, H.C.,Van Aalten, D.M.F. Screening-Based Discovery of Drug-Like O-Glcnacase Inhibitor Scaffolds FEBS Lett., 584:694-, 2010 Cited by PubMed: 20026047DOI: 10.1016/J.FEBSLET.2009.12.020 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.25 Å) |
Structure validation
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