2WNP

M-ficolin mutant Y271F

Summary for 2WNP

Entry DOI	10.2210/pdb2wnp/pdb
Related	2JHH 2JHI 2JHK 2JHL 2JHM
Descriptor	FICOLIN-1, CALCIUM ION, ISOPROPYL ALCOHOL, ... (4 entities in total)
Functional Keywords	glycoprotein, innate immunity, fibrinogen-like domain, carbohydrate recognition, lectin, immune system
Biological source	HOMO SAPIENS (HUMAN)
Cellular location	Secreted: O00602
Total number of polymer chains	1
Total formula weight	24329.99
Authors	Gout, E.,Garlatti, V.,Smith, D.F.,Lacroix, M.,Dumestre-Perard, C.,Lunardi, T.,Arlaud, G.J.,Gaboriaud, C.,Thielens, N.M. (deposition date: 2009-07-16, release date: 2009-12-22, Last modification date: 2023-12-13)
Primary citation	Gout, E.,Garlatti, V.,Smith, D.F.,Lacroix, M.,Dumestre-Perard, C.,Lunardi, T.,Martin, L.,Cesbron, J.Y.,Arlaud, G.J.,Gaboriaud, C.,Thielens, N.M. Carbohydrate Recognition Properties of Human Ficolins: Glycan Array Screening Reveals the Sialic Acid Binding Specificity of M-Ficolin. J.Biol.Chem., 285:6612-, 2010 Cited by PubMed: 20032467 DOI: 10.1074/JBC.M109.065854 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.21 Å)

Structure validation