2WNP
M-ficolin mutant Y271F
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA F 1298 |
| Chain | Residue |
| F | ASP233 |
| F | ASP235 |
| F | SER237 |
| F | SER239 |
| F | HOH2161 |
| F | HOH2163 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE IPA F 1299 |
| Chain | Residue |
| F | TYR283 |
| F | HOH2243 |
| F | CYS254 |
| F | HIS255 |
| F | ALA272 |
Functional Information from PROSITE/UniProt
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 39 |
| Details | Region: {"description":"A domain; contributes to trimerization"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 88 |
| Details | Region: {"description":"B domain; contributes to trimerization"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 9 |
| Details | Region: {"description":"P domain","evidences":[{"source":"PubMed","id":"17148457","evidenceCode":"ECO:0000303"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"17148457","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"17897951","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"20032467","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2D39","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2WNP","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"17897951","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 1 |
| Details | Site: {"description":"Mediates specificity for sialic acids","evidences":[{"source":"PubMed","id":"17897951","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"20032467","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 1 |
| Details | Site: {"description":"Mediates specificity for sialic acids","evidences":[{"source":"PubMed","id":"17897951","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI8 |
| Number of Residues | 1 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
