2W3Q
Structure and inhibition of the CO2-sensing carbonic anhydrase Can2 from the pathogenic fungus Cryptococcus neoformans
Summary for 2W3Q
Entry DOI | 10.2210/pdb2w3q/pdb |
Related | 2W3N |
Descriptor | CARBONIC ANHYDRASE 2, ZINC ION, CHLORIDE ION, ... (4 entities in total) |
Functional Keywords | beta-class carbonic anhydrase, lyase, inhibition, sulfonamide, cryptococcus neoformans |
Biological source | CRYPTOCOCCUS NEOFORMANS |
Total number of polymer chains | 1 |
Total formula weight | 27086.45 |
Authors | Schlicker, C.,Hall, R.A.,Vullo, D.,Middelhaufe, S.,Gertz, M.,Supuran, C.T.,Muehlschlegel, F.A.,Steegborn, C. (deposition date: 2008-11-14, release date: 2008-12-30, Last modification date: 2023-12-13) |
Primary citation | Schlicker, C.,Hall, R.A.,Vullo, D.,Middelhaufe, S.,Gertz, M.,Supuran, C.T.,Muehlschlegel, F.A.,Steegborn, C. Structure and Inhibition of the Co(2)-Sensing Carbonic Anhydrase Can2 from the Pathogenic Fungus Cryptococcus Neoformans. J.Mol.Biol., 385:1207-, 2009 Cited by PubMed: 19071134DOI: 10.1016/J.JMB.2008.11.037 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.34 Å) |
Structure validation
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