2V8F

Mouse Profilin IIa in complex with a double repeat from the FH1 domain of mDia1

Summary for 2V8F

Entry DOI	10.2210/pdb2v8f/pdb
Related	2V8C
Descriptor	PROFILIN-2, PROTEIN DIAPHANOUS HOMOLOG 1, SULFATE ION, ... (7 entities in total)
Functional Keywords	alternative splicing, protein-binding, cytoplasm, acetylation, cytoskeleton, actin-binding, protein binding
Biological source	MUS MUSCULUS (HOUSE MOUSE) More
Cellular location	Cell membrane: O08808
Total number of polymer chains	3
Total formula weight	32791.34
Authors	Kursula, P.,Kursula, I.,Downer, J.,Witke, W.,Wilmanns, M. (deposition date: 2007-08-07, release date: 2007-12-18, Last modification date: 2023-12-13)
Primary citation	Kursula, P.,Kursula, I.,Massimi, M.,Song, Y.H.,Downer, J.,Stanley, W.A.,Witke, W.,Wilmanns, M. High-Resolution Structural Analysis of Mammalian Profilin 2A Complex Formation with Two Physiological Ligands: The Formin Homology 1 Domain of Mdia1 and the Proline-Rich Domain of Vasp. J.Mol.Biol., 375:270-, 2008 Cited by PubMed: 18001770 DOI: 10.1016/J.JMB.2007.10.050 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.1 Å)

Structure validation