2V5E
The structure of the GDNF:Coreceptor complex: Insights into RET signalling and heparin binding.
Summary for 2V5E
Entry DOI | 10.2210/pdb2v5e/pdb |
Related | 1AGQ |
Related PRD ID | PRD_900013 |
Descriptor | GDNF FAMILY RECEPTOR ALPHA-1, GLIAL CELL LINE-DERIVED NEUROTROPHIC FACTOR, 1,3,4,6-tetra-O-sulfo-beta-D-fructofuranose-(2-1)-2,3,4,6-tetra-O-sulfonato-alpha-D-glucopyranose, ... (6 entities in total) |
Functional Keywords | receptor-glycoprotein complex, alternative splicing, cell membrane, growth factor, ligand-coreceptor, gpi-anchor, lipoprotein, polymorphism, glycoprotein, membrane, receptor, secreted, gfralpha1, cleavage on pair of basic residues, receptor-glycoprotein complex complex, receptor/glycoprotein complex |
Biological source | RATTUS NORVEGICUS (NORWAY RAT) More |
Total number of polymer chains | 2 |
Total formula weight | 35421.03 |
Authors | Parkash, V.,Leppanen, V.-M.,Virtanen, H.,Jurvansuu, J.-M.,Bespalov, M.M.,Sidorova, Y.A.,Runeberg-Roos, P.,Saarma, M.,Goldman, A. (deposition date: 2008-10-03, release date: 2008-10-21, Last modification date: 2023-12-13) |
Primary citation | Parkash, V.,Leppanen, V.-M.,Virtanen, H.,Jurvansuu, J.-M.,Bespalov, M.M.,Sidorova, Y.A.,Runeberg-Roos, P.,Saarma, M.,Goldman, A. The Structure of the Glial Cell Line-Derived Neurotrophic Factor-Coreceptor Complex: Insights Into Ret Signaling and Heparin Binding. J.Biol.Chem., 283:35164-, 2008 Cited by PubMed: 18845535DOI: 10.1074/JBC.M802543200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.35 Å) |
Structure validation
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