2V5E
The structure of the GDNF:Coreceptor complex: Insights into RET signalling and heparin binding.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | GDNF FAMILY RECEPTOR ALPHA-1 | polymer | 200 | 22538.6 | 1 | UniProt (Q62997) Pfam (PF02351) | RATTUS NORVEGICUS (NORWAY RAT) | GFR-ALPHA-1, GDNF RECEPTOR ALPHA, GDNFR-ALPHA, TGF-BETA-RELATED NEUROTROPHIC FACTOR RECEPTOR 1, RET LIGAND 1 |
| 2 | B (B) | GLIAL CELL LINE-DERIVED NEUROTROPHIC FACTOR | polymer | 101 | 11430.1 | 1 | UniProt (P39905) Pfam (PF00019) | HOMO SAPIENS (HUMAN) | ASTROCYTE-DERIVED TROPHIC FACTOR, HGDNF, ATF |
| 3 | C (C) | 1,3,4,6-tetra-O-sulfo-beta-D-fructofuranose-(2-1)-2,3,4,6-tetra-O-sulfonato-alpha-D-glucopyranose | branched | 982.8 | 1 | In PDB BIRD (PRD_900013) | sucrose octasulfate | ||
| 4 | D, E, F, G (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 4 | Chemie (EDO) | |||
| 5 | H (B) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) | |||
| 6 | I, J (A, B) | water | water | 18.0 | 223 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 33968.7 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 982.8 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 469.5 | |
| All* | Total formula weight | 35421.0 |
