2TGD
LACK OF THE TRANSITION STATE STABILIZATION SITE IS A FACTOR IN THE INACTIVITY OF TRYPSINOGEN, A SERINE PROTEASE ZYMOGEN. STRUCTURE OF DFP INHIBITED BOVINE TRYPSINOGEN AT 2.1 ANGSTROMS RESOLUTION
Summary for 2TGD
Entry DOI | 10.2210/pdb2tgd/pdb |
Descriptor | TRYPSINOGEN, CALCIUM ION, DIISOPROPYL PHOSPHONATE, ... (4 entities in total) |
Functional Keywords | hydrolase zymogen (serine proteinase) |
Biological source | Bos taurus (cattle) |
Cellular location | Secreted, extracellular space: P00760 |
Total number of polymer chains | 1 |
Total formula weight | 24219.19 |
Authors | Jones, M.O.,Stroud, R.M. (deposition date: 1986-03-17, release date: 1986-05-07, Last modification date: 2017-11-29) |
Primary citation | Jones, M.O.,Stroud, R.M. Lack of the Transition State Stabilization Site is a Factor in the Inactivity of Trypsinogen, a Serine Protease Zymogen. Structure of Dfp Inhibited Bovine Trypsinogen at 2.1 Angstroms Resolution To be Published, |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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