2REN
STRUCTURE OF RECOMBINANT HUMAN RENIN, A TARGET FOR CARDIOVASCULAR-ACTIVE DRUGS, AT 2.5 ANGSTROMS RESOLUTION
Summary for 2REN
Entry DOI | 10.2210/pdb2ren/pdb |
Descriptor | RENIN, 2-acetamido-2-deoxy-beta-D-glucopyranose (2 entities in total) |
Functional Keywords | hydrolase(acid proteinase) |
Biological source | Homo sapiens (human) |
Cellular location | Secreted: P00797 |
Total number of polymer chains | 1 |
Total formula weight | 37488.22 |
Authors | Sielecki, A.R.,James, M.N.G. (deposition date: 1992-02-05, release date: 1994-01-31, Last modification date: 2020-07-29) |
Primary citation | Sielecki, A.R.,Hayakawa, K.,Fujinaga, M.,Murphy, M.E.,Fraser, M.,Muir, A.K.,Carilli, C.T.,Lewicki, J.A.,Baxter, J.D.,James, M.N. Structure of recombinant human renin, a target for cardiovascular-active drugs, at 2.5 A resolution. Science, 243:1346-1351, 1989 Cited by PubMed: 2493678PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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