2QC1

Crystal structure of the extracellular domain of the nicotinic acetylcholine receptor 1 subunit bound to alpha-bungarotoxin at 1.9 A resolution

Summary for 2QC1

• Entry DOI: 10.2210/pdb2qc1/pdb
• Descriptor: Alpha-bungarotoxin, Acetylcholine receptor subunit alpha, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total)
• Functional Keywords: nicotinic acetylcholine receptor, glycosylated protein, beta sandwich, cys-loop, buried hydrophilic residues, protein binding
• Biological source: Mus musculus (house mouse); More
• Total number of polymer chains: 2
• Total formula weight: 34483.87

Authors

Dellisanti, C.D.,Yao, Y.,Stroud, J.C.,Wang, Z.,Chen, L. (deposition date: 2007-06-18, release date: 2007-08-07, Last modification date: 2023-08-30)

• Primary citation: Dellisanti, C.D.,Yao, Y.,Stroud, J.C.,Wang, Z.Z.,Chen, L.; Crystal structure of the extracellular domain of nAChR alpha1 bound to alpha-bungarotoxin at 1.94 A resolution.; Nat.Neurosci., 10:953-962, 2007; PubMed: 17643119; DOI: 10.1038/nn1942

Experimental method

X-RAY DIFFRACTION (1.94 Å)