2Q21
CRYSTAL STRUCTURES AT 2.2 ANGSTROMS RESOLUTION OF THE CATALYTIC DOMAINS OF NORMAL RAS PROTEIN AND AN ONCOGENIC MUTANT COMPLEXED WITH GSP
Replaces: 3P21Summary for 2Q21
Entry DOI | 10.2210/pdb2q21/pdb |
Descriptor | C-H-RAS P21 PROTEIN CATALYTIC DOMAIN, MAGNESIUM ION, GUANOSINE-5'-DIPHOSPHATE, ... (4 entities in total) |
Functional Keywords | oncogene protein |
Biological source | Homo sapiens (human) |
Cellular location | Cell membrane. Isoform 2: Nucleus: P01112 |
Total number of polymer chains | 1 |
Total formula weight | 20026.65 |
Authors | Kim, S.-H. (deposition date: 1991-09-25, release date: 1992-07-15, Last modification date: 2024-02-21) |
Primary citation | Tong, L.A.,de Vos, A.M.,Milburn, M.V.,Kim, S.H. Crystal structures at 2.2 A resolution of the catalytic domains of normal ras protein and an oncogenic mutant complexed with GDP. J.Mol.Biol., 217:503-516, 1991 Cited by PubMed: 1899707DOI: 10.1016/0022-2836(91)90753-S PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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