2Q21
CRYSTAL STRUCTURES AT 2.2 ANGSTROMS RESOLUTION OF THE CATALYTIC DOMAINS OF NORMAL RAS PROTEIN AND AN ONCOGENIC MUTANT COMPLEXED WITH GSP
Replaces: 3P21Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | C-H-RAS P21 PROTEIN CATALYTIC DOMAIN | polymer | 171 | 19559.1 | 1 | UniProt (P01112) Pfam (PF00071) In PDB | Homo sapiens (human) | |
| 2 | A | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 3 | A | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 1 | Chemie (GDP) | |||
| 4 | water | water | 18.0 | 40 | Chemie (HOH) |
Sequence modifications
A: 1 - 171 (UniProt: P01112)
| PDB | External Database | Details |
|---|---|---|
| Val 12 | Gly 12 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 19559.1 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 467.5 | |
| All* | Total formula weight | 20026.6 |
