2PRG
LIGAND-BINDING DOMAIN OF THE HUMAN PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA
Summary for 2PRG
Entry DOI | 10.2210/pdb2prg/pdb |
Descriptor | PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA, NUCLEAR RECEPTOR COACTIVATOR SRC-1, 2,4-THIAZOLIDIINEDIONE, 5-[[4-[2-(METHYL-2-PYRIDINYLAMINO)ETHOXY]PHENYL]METHYL]-(9CL), ... (4 entities in total) |
Functional Keywords | complex (thiazolidinedione-receptor), ligand-binding domain, nuclear receptor, apo, transcription factor, orphan receptor, complex (thiazolidinedione-receptor) complex, complex (thiazolidinedione/receptor) |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 3 |
Total formula weight | 72105.12 |
Authors | Nolte, R.T.,Wisely, G.B.,Milburn, M.V. (deposition date: 1998-08-14, release date: 1999-07-19, Last modification date: 2024-05-22) |
Primary citation | Nolte, R.T.,Wisely, G.B.,Westin, S.,Cobb, J.E.,Lambert, M.H.,Kurokawa, R.,Rosenfeld, M.G.,Willson, T.M.,Glass, C.K.,Milburn, M.V. Ligand binding and co-activator assembly of the peroxisome proliferator-activated receptor-gamma. Nature, 395:137-143, 1998 Cited by PubMed: 9744270DOI: 10.1038/25931 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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