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2PDP

Human aldose reductase mutant S302R complexed with IDD 393.

Summary for 2PDP
Entry DOI10.2210/pdb2pdp/pdb
Related2IKJ 2PD5 2PD9 2PDB 2PDC 2PDF 2PDG 2PDH 2PDI 2PDJ 2PDK 2PDL 2PDM 2PDN 2PDQ 2PDU 2PDW 2PDX 2PDY
DescriptorAldose reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, (5-CHLORO-2-{[(3-NITROBENZYL)AMINO]CARBONYL}PHENOXY)ACETIC ACID, ... (4 entities in total)
Functional Keywordstim barrel, oxidoreductase
Biological sourceHomo sapiens (human)
Cellular locationCytoplasm: P15121
Total number of polymer chains1
Total formula weight37076.60
Authors
Steuber, H.,Heine, A.,Klebe, G. (deposition date: 2007-04-01, release date: 2008-04-01, Last modification date: 2023-08-30)
Primary citationSteuber, H.,Heine, A.,Podjarny, A.,Klebe, G.
Merging the binding sites of aldose and aldehyde reductase for detection of inhibitor selectivity-determining features.
J.Mol.Biol., 379:991-1016, 2008
Cited by
PubMed: 18495158
DOI: 10.1016/j.jmb.2008.03.063
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.65 Å)
Structure validation

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