2OOA

crystal structure of the UBA domain from Cbl-b ubiquitin ligase

Summary for 2OOA

• Entry DOI: 10.2210/pdb2ooa/pdb
• Related: 2OO9 2OOB
• Descriptor: E3 ubiquitin-protein ligase CBL-B (2 entities in total)
• Functional Keywords: alpha-helical domain, ligase
• Biological source: Homo sapiens (human)
• Cellular location: Cytoplasm: Q13191
• Total number of polymer chains: 2
• Total formula weight: 11406.55

Authors

Kozlov, G.,Gehring, K. (deposition date: 2007-01-25, release date: 2007-02-06, Last modification date: 2023-12-27)

• Primary citation: Peschard, P.,Kozlov, G.,Lin, T.,Mirza, I.A.,Berghuis, A.M.,Lipkowitz, S.,Park, M.,Gehring, K.; Structural basis for ubiquitin-mediated dimerization and activation of the ubiquitin protein ligase Cbl-b.; Mol.Cell, 27:474-485, 2007; PubMed: 17679095; DOI: 10.1016/j.molcel.2007.06.023

Experimental method

X-RAY DIFFRACTION (1.56 Å)