2OOA
crystal structure of the UBA domain from Cbl-b ubiquitin ligase
Summary for 2OOA
Entry DOI | 10.2210/pdb2ooa/pdb |
Related | 2OO9 2OOB |
Descriptor | E3 ubiquitin-protein ligase CBL-B (2 entities in total) |
Functional Keywords | alpha-helical domain, ligase |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm: Q13191 |
Total number of polymer chains | 2 |
Total formula weight | 11406.55 |
Authors | Kozlov, G.,Gehring, K. (deposition date: 2007-01-25, release date: 2007-02-06, Last modification date: 2023-12-27) |
Primary citation | Peschard, P.,Kozlov, G.,Lin, T.,Mirza, I.A.,Berghuis, A.M.,Lipkowitz, S.,Park, M.,Gehring, K. Structural basis for ubiquitin-mediated dimerization and activation of the ubiquitin protein ligase Cbl-b. Mol.Cell, 27:474-485, 2007 Cited by PubMed: 17679095DOI: 10.1016/j.molcel.2007.06.023 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.56 Å) |
Structure validation
Download full validation report