2OO9

crystal structure of the UBA domain from human c-Cbl ubiquitin ligase

Summary for 2OO9

• Entry DOI: 10.2210/pdb2oo9/pdb
• Related: 2OOA 2OOB
• Descriptor: E3 ubiquitin-protein ligase CBL (2 entities in total)
• Functional Keywords: alpha-helical domain, homodimer, ligase
• Biological source: Homo sapiens (human)
• Cellular location: Cytoplasm: P22681
• Total number of polymer chains: 3
• Total formula weight: 15517.37

Authors

Kozlov, G.,Gehring, K. (deposition date: 2007-01-25, release date: 2007-02-06, Last modification date: 2023-12-27)

• Primary citation: Kozlov, G.,Peschard, P.,Zimmerman, B.,Lin, T.,Moldoveanu, T.,Mansur-Azzam, N.,Gehring, K.,Park, M.; Structural basis for UBA-mediated dimerization of c-Cbl ubiquitin ligase.; J.Biol.Chem., 282:27547-27555, 2007; PubMed: 17635922; DOI: 10.1074/jbc.M703333200

Experimental method

X-RAY DIFFRACTION (2.1 Å)