2MLE
NMR structure of the C-domain of troponin C bound to the anchoring region of troponin I
Summary for 2MLE
Entry DOI | 10.2210/pdb2mle/pdb |
Related | 2MLF |
NMR Information | BMRB: 19816 |
Descriptor | Troponin C, slow skeletal and cardiac muscles, CALCIUM ION (2 entities in total) |
Functional Keywords | troponin c, metal binding protein, troponin i, ef-hand, cardiac troponin |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 1 |
Total formula weight | 8449.36 |
Authors | Robertson, I.M.,Baryshnikova, O.K.,Mercier, P.,Sykes, B.D. (deposition date: 2014-02-26, release date: 2014-03-12, Last modification date: 2023-06-14) |
Primary citation | Baryshnikova, O.K.,Robertson, I.M.,Mercier, P.,Sykes, B.D. The dilated cardiomyopathy G159D mutation in cardiac troponin C weakens the anchoring interaction with troponin I. Biochemistry, 47:10950-10960, 2008 Cited by PubMed: 18803402DOI: 10.1021/bi801165c PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
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