2KFB
The structure of the cataract causing P23T mutant of human gamma-D crystallin
Summary for 2KFB
Entry DOI | 10.2210/pdb2kfb/pdb |
NMR Information | BMRB: 16173 |
Descriptor | Gamma-crystallin D (1 entity in total) |
Functional Keywords | crystallin, cataract, protein, lens, disease mutation, eye lens protein, oxidation, sensory transduction, vision, structural protein |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 1 |
Total formula weight | 21856.35 |
Authors | Jung, J.,Byeon, I.L.,Wang, Y.,King, J.,Gronenborn, A.M. (deposition date: 2009-02-12, release date: 2009-07-28, Last modification date: 2024-05-22) |
Primary citation | Jung, J.,Byeon, I.J.,Wang, Y.,King, J.,Gronenborn, A.M. The structure of the cataract-causing P23T mutant of human gammaD-crystallin exhibits distinctive local conformational and dynamic changes. Biochemistry, 48:2597-2609, 2009 Cited by PubMed: 19216553DOI: 10.1021/bi802292q PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
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